SYNERGISTIC EFFECT OF SUBTOXIC-DOSE CISPLATIN AND TRAIL TO MEDIATE APOPTOSIS BY DOWN-REGULATING DECOY RECEPTOR 2 AND UP-REGULATING CASPASE-8, CASPASE-9 AND BAX EXPRESSION ON NCI-H460 AND A549 CELLS

Objective(s): Although tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) can selectively induce apoptosis in tumor cells, more than half of tumors including non-small cell lung cancer (NSCLC) exhibit TRAIL-resistance.The purpose of this study was to determine whether subtoxic-dose cisplatin and TRAIL could synergistically enhance apop

Saman Ahmad Nasrollahi,1,* Maede Sabet Nematzadeh,2,* Aniseh Samadi,1 Azin Ayatollahi,1 Somayeh Yadangi,1 Christoph Abels,3 Alireza Firooz11Center for Research & Training in Skin Diseases & Leprosy, Tehran University of Medical Sciences, Tehran, Iran; 2Pharmaceutical Sciences Branch, Islamic Azad University, Tehran, Iran; 3Dr.August Wolff G

This article addresses the summative effects of the social crisis and the Covid-19 pandemic on the health-disease-care process Table Lamp Set at the level of Chilean society in the neoliberal context.The economy-health relationship is deepened, a phenomenon that is interpreted from the conceptual framework of necropolitics.The Differential retrauma

Abstract Background The olive tree is an oil-storing species, with pollen being the second most active site in storage lipid biosynthesis.Caleosins are proteins involved in storage lipid mobilization during seed germination.Despite the existence of different lipidic structures in the anther, there are no data regarding the presence of caleosins in